Nitric Oxide & Drug Releasing Polymers

Imagine an absorbable macromer or polymer that releases nitric oxide and drug simultaneously at a controlled rate while providing the functional performance you need to make your application as success. At Bezwada Biomedical, we not only imagined it, we have made it into a reality.

We are pleased to offer a portfolio of nitric oxide and drug releasing absorbable oligomers and polymers for technical evaluation and product development.

Key features and benefits include:

  • Rate of release of drug and NO as well as the amount released can be controlled
  • Hydrolysable linker repeat units derived from safe and biocompatible molecules
  • One and more than one NO releasing moiety per drug molecule are provided
  • NO and drug releasing polyurethanes and polyesters

Key Applications

  • Treatment of osteoarthritis, cardio metabolic and inflammatory disorders
  • Treatment of Glaucoma and diabetic
    macular edema
  • Wound healing and pain management
  • NO and drug eluting stents/coatings
  • Treatment of skin disorders

NITRIC-OXIDE-RELEASING DRUGS

Key Attributes

  • Drug molecules and NO releasing moiety attached via hydrolytically degradable linker
  • Controllable release profiles

Applications

  • Treatment of Glaucoma, Osteoarthritis, Cardio-metabolic and inflammatory disorders
  • NO releasing coatings

Patents

  • 8,303,978 Controlled release of nitric oxide and drugs from functionalized macromers and oligomers
  • 8,062,653┬áControlled release of nitric oxide and drugs from functionalized macromers and oligomers
  • EP2398761A2┬áControlled release of nitric oxide and drugs from functionalized macromers and oligomers
  • 8,802,147 Controlled release of biologically active compounds
  • 8,552,139 Controlled release of biologically active compounds
  • 8,409,559 Functionalized drugs and polymers derived therefrom
  • 8,217,134 Controlled release of biologically active compounds
  • 8,163,806 Controlled release of biologically active compounds from multiarmed oligomers
  • 8,026,285 Control release of biologically active compounds from multi-armed oligomers
  • 7,691,364 Functionalized drugs and polymers derived therefrom
  • RE45,548 Functionalized drugs and polymers derived therefrom

Polymers

Applications

How We Work

Biomaterials Innovators

15 Ilene Court
Suite 1
Hillsborough, NJ 08844

info@bezwadabiomedical.com

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