Functionalized Natural Products

We provide a portfolio of functionalized isoflavonoids which can be used either as polymers or monomers for extended and controlled release applications. The motivation to control the rate of release of the isoflavonoid molecules from few hours to months formed the basis for the development of novel absorbable oligomers of glycolide, lactide, p-dioxanone and caprolactone wherein the end groups have been functionalized with isoflavonoid molecules. Functionalized isoflavonoids are expected to release isoflavonoid molecule in a controlled manner at the site of action which will increase its efficacy over long period of time. It also helps increase the solubility of isoflavonoid and the release of the isoflavonoid molecules while preserving its therapeutic activity.