Functionalized Natural Products

We provide a portfolio of functionalized isoflavonoids which can be used either as polymers or monomers for extended and controlled release applications.

The motivation to control the rate of release of the isoflavonoid molecules from few hours to months formed the basis for the development of novel absorbable oligomers of glycolide, lactide, p-dioxanone and caprolactone wherein the end groups have been functionalized with isoflavonoid molecules. Functionalized isoflavonoids are expected to release isoflavonoid molecule in a controlled manner at the site of action which will increase its efficacy over long period of time. It also helps increase the solubility of isoflavonoid and the release of the isoflavonoid molecules while preserving its therapeutic activity.

Examples of Isoflavoniods Bezwada

Funtionalized Natural Products

Key Attributes

  • Derived from natural phenolic molecules such as flavonoids, chalcones and coumarins
  • Incorporates beneficial attributes of natural molecules in the polymer backbone
  • Tunable hydrolytic degradation profiles

Applications

  • Drug delivery
  • Cosmetics
  • Radiation-stable medical devices
  • Anti-microbial coatings

Patents

  • 8,802,892 Functionalized phenolic compounds and polymers therefrom
  • 8,372,882 Functionalized phenolic esters and amides and polymers therefrom
  • 8,318,973 Functionalized sinapic acid and methyl sinapate
  • 8,309,132 Bioabsorbable polyesteramides and uses thereof
  • 8,048,980 Hydrolysable linkers and cross-linkers for absorbable polymers
  • 8,007,526 Difunctionalized aromatic compounds and polymers therefrom
  • 7,902,319 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom
  • 7,85,8077 Functionalized phenolic esters and amides and polymers therefrom
  • 7,671,168 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom
  • 8,664,429 Hydrolysable linkers and cross-linkers for absorbable polymers
  • 9,045,396 Hydrolysable linkers and cross-linkers for absorbable polymers
  • 9,174,924 Hydrolysable linkers and cross-linkers for absorbable polymers

Polymers

Applications

How We Work

Biomaterials Innovators

15 Ilene Court
Suite 1
Hillsborough, NJ 08844

info@bezwadabiomedical.com

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