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Categories: All | Absorbable Polymer Properties | Bioprinting | Implantable Medical Devices
Controlled Drug Delivery with Biodegradable Polymers
Localized drug delivery continues to gain traction over systemic drugs as it allows for higher potency and reduced side effects. For example, cancer treatment efficacy depends on the dose of the drug that reaches the tumor, and polymer wafers, nanofibrous scaffolds, and hydrogels have been used for localized drug delivery (Woodring et al., ACS Appl Bio Mater. 2023).
Biodegradable Polyurethanes
Polyurethanes are increasingly becoming the biomaterial of choice for biomedical applications due to their superior mechanical strength, biocompatibility, abrasion resistance, and manufacturability.
There are two main categories of medical grade polyurethanes: biostable and biodegradable. Biostable polyurethanes are used in medical devices such as catheters, infusion pumps, and cardiac pacemakers. Absorbable polyurethanes are an emerging biomaterial used for implantable medical devices in wound healing, cardiovascular, musculoskeletal, and neural repair applications.
3D Printed Bioresorbable Implantable Devices
The flexibility of 3D printing your biodegradable medical device is appealing. Lower manufacturing costs, fast and efficient production, customized designs to fit individualized patient anatomy, and opportunity for point of care manufacturing. But you also need to find the right material that will work with your 3D printer and meet your implantable device requirements…
Striking the right balance between bioabsorbable polymer strength and degradation rate
Bioabsorbable polymers are designed to be there when you need them and gone when you don’t need them anymore. But striking the right balance between adequate mechanical strength during the medical device’s useful life and suitable degradation rate can be challenging.
If the polymer degrades too fast, the device will lack the required mechanical integrity…
Change is Hard: How to make the switch to a different bioabsorbable polymer for your approved/cleared device.
After years in development, your medical device was finally approved or cleared by the FDA and is now on the market. Whether your device was 100% or partially made with a synthetic bioabsorbable polymer, you probably had to compromise with the polymer properties and functional performance because you could not find a polymer that met all your design requirements…
Absorbable Polymer Inks for 3D Printing
Whether you’re manufacturing 3D printers or just bought a shiny new 3D printer to work with, even the best one can be rather useless without the right ink.
What’s the right ink? Only you know that. You know the material properties you’d like to have and what the printed part should be able to do, and not do, but finding a polymer that meets those requirements is easier said than done…
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