Controlled Drug Delivery
Key features and benefits of these drug delivery polymers include:
- Drug molecule is a part of polymer backbone resulting in delivery of highly effective and potent dose
- Completely hydrolysable into safe and biocompatible products and drug molecule as such at the site of action
- Tunable rate of release leading to no-burst effects in delivery
- No need to use excipients or solubility modifiers
- Gamma and EtO sterilizable
Key Applications
- Advanced Wound Repair
- Sports Injuries
- Topical analgesic and anti-inflammatory creams
- Medical Device Coatings
- Arthritis and Pain management
- Veterinary applications
Localized, delayed, and prolonged drug release is highly desirable in the delivery of many therapeutics. Biodegradable polymers are used for controlled drug release to the buccal mucosa in oral applications, the central nervous system, to brain tumors through intracranial implantations, the vasculature through drug eluting stents and grafts, spinal fusion surgeries, and wound sites.
In orthopedic and spinal applications, bone morphogenetic protein-2 and other growth factors are often delivered through local and sustained release for bone regeneration to injured or diseased bones. In wound healing, antimicrobial drugs, analgesics, and hemostatic agents are often delivered to wound sites and through burn wound dressings.
Each controlled drug release indication has specific requirements that require flexibility and innovation in the medical device design. Bezwada’s expertise and product breadth are well-suited for meeting the most stringent design requirements.
Controlled Drug Delivery Patents
- 8,802,147 Controlled release of biologically active compounds
- 8,552,139 Controlled release of biologically active compounds
- 8,409,559 Functionalized drugs and polymers derived therefrom
- 8,217,134 Controlled release of biologically active compounds
- 8,163,806 Controlled release of biologically active compounds from multiarmed oligomers
- 8,026,285 Control release of biologically active compounds from multi-armed oligomers
- 7,691,364 Functionalized drugs and polymers derived therefrom
- RE45, 548 Functionalized drugs and polymers derived therefrom
- 8,303,978 Controlled release of nitric oxide and drugs from functionalized macromers and oligomers
- 8,062,653 Controlled release of nitric oxide and drugs from functionalized macromers and oligomers
- EP2398761A2 Controlled release of nitric oxide and drugs from functionalized macromers and oligomers
- 8,399,696 Functionalized biodegradable triclosan monomers and oligomers for controlled release
- 8,232,422 Functionalized biodegradable triclosan monomers and oligomers for controlled release
- 8,053,591 Functionalized biodegradable triclosan monomers and oligomers for controlled release
Polymers
Applications
How We Work
Absorbable Biomaterials Innovators
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